In a study of over 89,000 adults hospitalized with COVID-19 symptoms, prior vaccination with two doses of the Pfizer or Moderna vaccine was 77% effective in preventing COVID-19 in immunocompromised patients compared with 90% effective in immunocompetent patients, the Centers for Disease Control and Prevention reported today. The authors recommend three doses and a booster for immunocompromised individuals receiving mRNA COVID-19 vaccines, consistent with CDC recommendations.

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